Alzheimer’s Gene Effects Show Up in InfancyThe Alzheimer's Site
While genetics is no guarantee that individuals will develop Alzheimer’s, a new discovery revealed that infants and toddlers with the Alzheimer’s disease-associated APOE4 genotype already showed distinctive patterns of brain structure relative to other young children.
“While our findings should be considered preliminary, this study demonstrates some of the earliest brain changes associated with the major genetic risk factor for late-onset Alzheimer’s disease,” the researchers wrote online in JAMA Neurology.
This is a huge breakthrough in being able to judge early predictors of the disease and identify at-risk individuals long before they show any classic symptoms linked with Alzheimer’s. It also opens up the possibility of discovering correlations between genetics and developing nervous systems that eventually converge into Alzheimer’s disease.